CHENG, YUNG-SUNG, PHD

EDUCATION
B.S. (Chemical Engineering) 1969, National Taiwan University
M.S. (Chemical Engineering) 1973, Syracuse University
Ph.D. (Chemical Engineering) 1976, Syracuse University
Postdoctoral Fellow, 1976-1978, Aerosol Science, University of Rochester
 


EMPLOYMENT

1996 - Present Senior Scientist; Director of Aerosol and Respiratory Dosimetry Program, Lovelace Respiratory Research Institute, Albuquerque, NM
1996 - Present Clinical Professor, College of Pharmacy, University of New Mexico, Albuquerque, NM
1992 - 1996 Clinical Associate Professor, College of Pharmacy, University of New Mexico, Albuquerque, NM
1991 - 1996 Aerosol Program Manager, Inhalation Toxicology Research Institute, Albuquerque, NM
1988 - 1991 Supervisor, Chronic Exposure Laboratory Section, Inhalation Toxicology Research Institute, Albuquerque, NM
1978 - 1984 Aerosol Engineer, Inhalation Toxicology Research Institute, Albuquerque, NM


PROFESSIONAL AFFILIATIONS
Chairman, Aerosol Technology Committee, American Industrial Hygiene Association, 1987-1988
Member, Air Sampling Instrument Committee, American Conference of Governmental Industrial
     Hygienist, 1988-Present
President, NM chapter, Chinese Institute of Engineers, 1996-1997
Associate Editor, Aerosol Science and Technology, 1999-2003
Conference Chair, American Association for Aerosol Research, 2001
Board of Directors, American Association for Aerosol Research, 2001-2004
President, Oversea Chinese Environmental Engineers and Scientists Assoc., 2005
Secretary, American Association for Aerosol Research, 2005-2007
Member, Editorial Board, Aerosol and Air Quality Research, 2006-2008
Member, Editorial Board, Journal of Environmental Research and Public Health, 2007-
Member, Committee on Determining a Standard Unit of Measure for Biological Aerosols, the
     National Academy, 2007
Treasurer, National Council, Chinese Institute of Engineers, USA, 2008-2010
Vice President, National Council, Chinese Institute of Engineers, USA, 2010-2011
Fellow, American Association for Aerosol Research, 2008-
Member, External Advisor Committee, Center of Excellence, University of Alabama at
     Birmingham, 2009-



AREAS OF RESEARCH
Dr. Cheng's research interests are centered in the following areas: 1) aerosol drug delivery; 2) design and test of air sampling instruments; 3) deposition in the respiratory tract; 4) air quality of ambient, occupational and indoor environments; 5) measurement of radon and radon progeny; and 6) inhalation toxicology. He is particularly interested in characteristics of airborne material that will influence its transport, collection, deposition and retention in human and environments. Dr. Cheng has been heavily involved in the design and operation of high-quality systems for animal inhalation exposure studies. More recently, he has been conducting studies on aerosol deposition in the nasal, oral and conducting airways, especially for those ultrafine particles and fiber aerosol. Pharmaceutical aerosol delivery system from formulation, design and evaluation of devices, deposition, and preclinical trials are also current research activities. Wind tunnel testing of air sampling instruments is also a focus of the research activities.

 

ACCESS THIS AUTHOR'S PUBLICATIONS IN PUBMED
 



RECENT PUBLICATIONS

  1. Su, W. C., J. Wu, J. C. M. Marijnissen and Y. S. Cheng: Deposition of Man-made Fibers in the Human Nasal Airway. Aerosol Sci. Technol. 42(3): 173-181, 2008.

     

  2. Zhou, Y., W. C. Su and Y. S. Cheng: Fiber Deposition in the Tracheobronchial Region: Deposition Equations. Inhal. Toxicol. 20(13): 1191-1198, 2008.

     

  3. Backer, L. C., S. V. McNeel, T. Barber, B. Kirkpatrick, C. Williams, M. Irvin, Y. Zhou, T. B. Johnson, K. Nierenberg, M. Aubel, R. LePrell, A. Chapman, A. Foss, S. Corum, V. R. Hill, S. M. Kieszak and Y. S. Cheng: Recreational Exposure to Microcystins During Algal Blooms in Two California Lakes. Toxicon Jul 15 [Epub ahead of print], 2009.

     

  4. Cheng, Y.-S., J. L. Kenoyer, R. Guilmette and M. A. Parkhurst: Physicochemical Characterization of Capstone Depleted Uranium Aerosols II: Particle Size Distributions as a Function of Time. Health Phys. 96(3): 266-275, 2009.

     

  5. Cheng, Y. S., Y. Zhou, R. H. Pierce, M. Henry and D. G. Baden: Characterization of Florida Red Tide Aerosol and the Temporal Profile of Aerosol Concentration. Toxicon Oct 29 [Epub ahead of print], 2009.

     

  6. Fleming, L. E., J. A. Bean, B. Kirkpatrick, Y. S. Cheng, R. Pierce, J. Naar, K. Nierenberg, L. C. Backer, A. Wanner, A. Reich, Y. Zhou, S. Watkins, M. Henry, J. Zaias, W. M. Abraham, J. Benson, A. Cassedy, J. Hollenbeck, G. Kirkpatrick, T. Clarke and D. G. Baden: Exposure and Effects Assessment of Aerosolized Red Tide Toxins (Brevetoxins) and Asthma. Environ. Health Perspect. 117(7): 1095-1100, 2009.

     

  7. Guilmette, R. A. and Y. S. Cheng: Physicochemical Characterization of Capstone Depleted Uranium Aerosols IV: In vitro Solubility Analysis. Health Phys. 96(3): 292-306, 2009.

     

  8. Holmes, T. D., R. A. Guilmette, Y. S. Cheng, M. A. Parkhurst and M. D. Hoover: Aerosol Sampling System for Collection of Capstone Depleted Uranium Particles in a High-Energy Environment, Health Phys. 96(3): 221-237, 2009.

     

  9. Lin, H.-L., J. B. Fink, Y. Zhou and Y. S. Cheng: Influence of Moisture Accumulation in Inline Spacer on Delivery of Aerosol Using Metered-Dose Inhaler During Mechanical Ventilation. Respir. Care 54(10): 1336-1341, 2009.

     

  10. Miller, G., Y.-S. Cheng, R. T. Traub, T. T. Little and R. A. Guilmette: Methods Used to Calculate Doses Resulting from Inhalation of Capstone Depleted Uranium Aerosols. Health Phys. 96(3): 306-327, 2009.

     

  11. Parkhurst, M. A., Y. S. Cheng, J. L. Kenoyer and R. J. Traub: Physicochemical Characterization of Capstone Depleted Uranium Aerosols I: Uranium Concentration in Aerosols as a Function of Time and Particle Size. Health Phys. 96(3): 251-265, 2009.

     

  12. Su, W. C. and Y. S. Cheng: Deposition of Man-made Fibers in Human Respiratory Airway Casts. J. Aerosol Sci. 40(3): 270-284, 2009.

     

  13. Weber, W. M., D. A. Kracko, M. R. Lehman, C. M. Irvin, L. F. Blair, R. K. White, J. M. Benson, G. R. Grotendorst, Y. S. Cheng and J. D. McDonald: Inhalation Exposure Systems for the Development of Rodent Models of Sulfur Mustard-Induced Pulmonary Injury. Toxicol. Mech. Methods Dec 21 [Epub ahead of print], 2009.

     

  14. Kirkpatrick, B., R. Pierce, Y. S. Cheng, M. S. Henry, P. Blum, S. Osborn, K. Nierenberg, B. A. Pederson, L. E. Fleming, A. Reich, J. Naar, G. Kirkpatrick, L. C. Backer and B. Baden: Inland Transport of Aerosolized Florida Red Tide Toxins. Harmful Algae 9(2): 186-189, 2010.

     

  15. Tolchinsky, A. D., V. I. Sigaev, G. I. Sigaev, A. N. Varfolomeev, E. V. Zvyagina, T. Brasel and Y. S. Cheng: Development of a Personal Bioaerosol Sampler Based on a Conical Cyclone with Recirculating Liquid Film. J. Occup. Environ. Hyg. 7(3): 156-162, 2010.

     

  16. Weber, W. M., D. A. Kracko, M. R. Lehman, C. M. Irvin, L. F. Blair, R. K. White, J. M. Benson, G. R. Grotendorst, Y. S. Cheng and J. D. McDonald: Inhalation Exposure Systems for the Development of Rodent Models of Sulfur Mustard-Induced Pulmonary Injury. Toxicol. Mech. Methods 20(1): 14-24, 2010.

     

  17. Zhou, Y. and Y. S. Cheng: Evaluation of IOM Personal Sampler at Different Flow Rates. J. Occup. Environ. Hyg. 7(2): 88-93, 2010.

     

  18. Zhou, Y., Y. S. Cheng and Y. Wang: Dissolution Rate and Biokinetic Model of Zirconium Tritide Particles in Rat Lungs. Health Phys. 98(5): 672-682, 2010.

     

  19. Weber, W. M., D. A. Kracko, M. R. Lehman, C. E. Cox, Y.-S. Cheng, G. R. Grotendorst and J. D. McDonald: Dermal and Ocular Exposure Systems for the Development of Models of Sulfur Mustard-Induced Injury. Toxicol. Mech. Methods Apr 8 [Epub ahead of print], 2011.       

     
  20. Cheng, Y. S., Y. Zhou, R. H. Pierce, M. Henry and D. G. Baden:  Characterization of Florida Red Tide Aerosol and the Temporal Profile of Aerosol Concentration.  Toxicon 55(5): 922-929, 2010. PMCID: PMC28377

     

  21. ​Cheng, Y. S., Y. Zhou, J. Naar, C. M. Irvin, W. C. Su, L. E. Fleming, B. Kirkpatrick, R. H.  Pierce, L. C. Backer and D. G. Baden:  Personal Exposure to Aerosolized Red Tide Toxins (Brevetoxins).  J. Occup. Environ. Hyg. 7(6): 326-331, 2010.

     

  22. Jiang, X., T. L. Ward, Y. S. Cheng, J. Liu and C. J. Brinker:  Aerosol Fabrication of Hollow Mesoporous Silica Nanoparticles and Encapsulation of L-Methionine as a Candidate Drug Cargo.  Chem. Commun. (Camb.) 46(17): 3019-3021, 2010.

     

  23. Backer, L. C., S. V. McNeel, T. Barber, B. Kirkpatrick, C. Williams, M. Irvin, Y. Zhou, T. B. Johnson, K. Nierenberg, M. Aubel, R. LePrell, A. Chapman, A. Foss, S. Corum, V. R. Hill, S. M. Kieszak and Y. S. Cheng:  Recreational Exposure to Microcystins During Algal Blooms in Two California Lakes.  Toxicon 55(5): 909-921, 2010.

     

  24. Cheng, Y. S., L. Bowen, R. J. Rando and E. M. Postlethwait:  Exposing Animals to Oxidant Gases:  Nose Only vs. Whole Body.  Proc. Am. Thorac. Soc. 7: 264-268, 2010.

     

  25. Kirkpatrick, B., L. E. Fleming, J. A. Bean, K. Nierenberg, L. C. Backer, Y. S. Cheng, R. H. Pierce, A. Reich, J. Naar, A. Wanner, W. M. Abraham and D. G. Baden:  Aerosolized Red Tide Toxins (Brevetoxins) and Asthma:  Continued Health Effects After 1 Hour Beach Exposure.  Harmful Algae 10(1): 138-147, 2011.

     

  26. Fleming,L.E.,Kirkpatrick, B., Backer, L.C., Walsh, C.J., Nierenberg, K.,Clark, J., Reich, A., Hollenbeck, J., Benson, J., Cheng, Y.S., Naar, J., Pierce, R., Bourdelais, A.J., Abraham, W.M., Kirkpatrick, G., Zaias, J., Wanner, A., Mendes, E., Shalat, S., Hoagland, P., Stephan, W., Bean, J., Watkins, S., Clarke, T., Byrne, M., Baden, D.G.: Review of Florida Red Tide and Human Health.  Harmful Algae 10(1): 224-233, 2011.

     

  27. Pierce, R.H., Henry, M.S., Blum, P.C. Osborn, S.E., Cheng, Y.S., Zhou, Y., Irvin, C.M.,  Bourdelais, A.J., Naar, J., and Baden, D.G.: Compositional Changes in Neurotoxins and Their Oxidative Derivatives from the Dinoflagellate, Karenia brevis, in Seawater and Marine Aerosol. J. Plankton Res. 33(2):343-348, 2011.

     

  28. Bean, J.A., Fleming, L.E., Kirkpatrick, B., Backers, L.C., Nierenberg, K., Reich, A., Cheng, Y.S., Wanners, A., Benson, J., Naar, J., Pierce, R., Abraham, W.M., Kirkpatrick, G., Hollenbeck, J., Zaias, J., Mendes, E., and Baden, D.G.:  Florida Red Tide Toxins (Brevetoxins) and Longitudinal Respiratory Effects in Asthmatics.  Harmful Algae 10:744-748, 2011.

     

  29. Jiang, X., Cheng, Y.S., and Smyth, H.D.C.: Nanostructured Aerosol Particles: Fabrication, Pulmonary Drug Delivery, and Controlled Release. J. Nanomaterials, Volume 2011, Article ID 198792, 2011.

     

  30. Tolchinsky, A.D., Sigaev, V.I., Varolomev, A.N., Zvyagina, E.V., Cheng, Y.S., and Su, W.C.: Performance Evaluation of Two Personal Bioaerosol Samplers. J. Environ. Sci. and Health, Part A. 46:1690-1698, 2011.

     

  31. Zhou, Y., Sun, J.J., and Cheng, Y.S.: Comparison of Deposition in the USP and Physical Mouth-Throat   Models with Solid and Liquid Particles.  J. Aerosol Med. Pulmon. Drug Delivery 24(6): 277-284, 2011.

     

  32. MacInnes, H., Zhou, Y., Gouveia, K., Cromwell, J., Lowery, K., Layton, R.C., Van Westrienen, J.C., Zubelewicz, M., Sampath, R., Hofstadler, S., Cawthon, A., Cheng, Y.S., Koster, F.: Transmission of Aerosolized Seasonal Influenza A to Ferrets. PoLS one 6(9): e24448, 2011.

     

  33. Jiang, X., Bao, L., Cheng, Y. S., Dunphy, D. R., Li, X., Brinker, C. J.: Aerosol-assisted synthesis of monodisperse single-crystalline alpha-cristobalite nanospheres. Chem Commun (Camb) 48, 1293-5, 2012.

     

  34. Koster, F. Gouveia, K., Zhou, Y., Lowery, K., Russell, R., MacInnes, H., Pollack, Z.  Layton, R.C., Cromwell, J., Toleno, D., Pyle, J., Zubelewicz, M., Harrod, K., Sampath, R., Hofstadler, S., Gao, P., Liu, Y., and Cheng, Y.S.:  Exhaled Aerosol Transmission of Pandemic and Seasonal H1N1 Influenza Virus in the Ferret.  PoLS one  7(4): e33118, 2012.