EDUCATION
 D.V.M. (Veterinary Medicine) 1993, Addis Ababa University, Ethiopia
 M.S. Excellent (Veterinary Epidemiology) 1998, Free University of Berlin, Germany/Addis
      Ababa University, Ethiopia
 Ph.D. magna cum laude (Molecular Epidemiology/Parasitology) 2005, Free University
      of Berlin, Germany
 

EMPLOYMENT

HONORS AND AWARDS
 Scholarship from "Katholischer Akademisher Auslaender-Dienst," 1996-1998
 Scholarship from "Katholischer Akademisher Auslaender-Dienst," 2002-2005
 Young Investigator Travel Award, American Thoracic Society (ATS), May 2008

 
 PROFESSIONAL AFFILIATIONS
 American Thoracic Society
 Ethiopian Veterinary Association
 
 AREAS OF RESEARCH
 Dr. Mebratu is interested in investigating the roles of airway inflammation and remodeling in various lung disorders such as asthma and chronic bronchitis. The responses of airway epithelial cells to inflammation or insult are key to understanding the remodeling process. He is investigating the intracellular signaling pathways regulating biological processes such as apoptosis that are involved in maintaining homeostasis.

ACCESS THIS AUTHOR'S PUBLICATIONS IN PUBMED
 
 

REPRESENTATIVE PUBLICATIONS AND POSTER PRESENTATIONS
 (Also published under the names Y. Afework and Y. Afework Mebratu.)

1. Afework, Y.: Field Investigations of the Appearance of Drug Resistant Population of Trypanosomes in Metekel District, Northwest Ethiopia. MSc Thesis, Freie Universität Berlin and Addis Ababa University, January 1998.

    

2. Afework, Y., P.-H. Clausen, G. Abebe, G. Tilahun and D. Mehlitz: Appearance of Multiple Drug Resistant Trypanosome Populations in Metekel District, Northwest Ethiopia. Acta Trop. 76: 231 238, 2000.

    

3. Afework, Y., P.-H. Clausen, G. Abebe, G. Tilahun and M. Dieter: Appearance of Multiple Drug Resistant Trypanosome Populations in Village Cattle of Metekel District, Northwest Ethiopia. In Proceedings of the 10th International Conference of the Association of Institutions for Tropical Veterinary Medicine, Copenhagen, Denmark, 2001.

    

4. Afework, Y., A. Tegegn and T. Kassa: Evaluation of the Productive and Reproductive Performances of Arsi X Friesian Crossbred Cows at Assela Livestock Research Station. Ethiopian Journal of Animal Production 1: 1-11, 2001.

    

5. Afework, Y.: Background Information on Contagious Bovine Pleuro Pneumonia (CBPP) in Ethiopia. Consultancy work to the Organization of African Unity Inter African Bureau for Animal Resources (OAU/IBAR), Nairobi, Kenya, December 2001.

    

6. Tewelde, N., G. Abebe, M. Eisler, J. McDermott, M. Greiner, Y. Afework, M. Kyule, S. Münstermann, K.-H. Zessin and P.-H. Clausen: Application of Field Methods to Assess Isometamidium Resistance of Trypanosomes in Cattle in Western Ethiopia. Acta Trop. 90: 163 170, 2004.

    

7. Afework Mebratu, Y.: Parasitological and Molecular Characterisation of Isometamidium-Sensitive and -Resistant Trypanosoma congolense and T. brucei brucei Isolates from Cattle in East and West Africa. Ph.D. Thesis, Mensch & Buch Verlag, Berlin. - V. 149 S. Zugl.: Berlin, Freie Univ., Diss. ISBN:3-89820-944-X, 2005.

    

8. Afework Mebratu, Y., B. Etschmann, G. von Samson-Himmelstjerna and P.-H. Clausen: Variations in TbAT1 Gene Sequences Between Isometamidium Chloride Sensitive and Resistant Trypanosoma brucei brucei. Tagung der DVG-Fachgruppe. Potsdam, Germany, 22.-24.6.2005. Diagnostik, Epidemiologie und Bekämpfung von Parasitosen bei Ntuz-, Haus- und Heimtieren. Mensch & Buch Verlag, Berlin. - S. 55. ISBN:3-89820-907-5, 2005.

    

9. Afework Mebratu, Y., B. Etschmann, G. von Samson-Himmelstjerna, K.-H. Zessin and P.-H. Clausen: PCR-RFLP in TbAT1 Transporter Gene b/n Isometamidium-Sensitive and -Resistant Stocks of T. brucei brucei. Research Coordinated Meeting on “Developing, Validating and Standardizing Methodologies for the Use of PCR and PCR-ELISA in the Diagnosis and Monitoring of Control and Eradication Programs for Trypanosomosis,” International Atomic Energy Agency (IAEA), Hanoi, Vietnam, June 20-24, 2005.

    

10. Afework, Y., P. Mäser, B. Etschmann, G. von Samson-Himmelstjerna, K.-H. Zessin and P. H. Clausen: Rapid Identification of Isometamidium-Resistant Stocks of Trypanosoma b. brucei by PCR-RFLP. Parasitol. Res. 99(3): 253-261, 2006.

     

11. Mebratu, Y. A., B. Dickey, C. Evans, M. Schuyler and Y. Tesfaigzi: Bik-Mediated ERK Activation is Central for IFNg-Induced Cell Death of Hyperplastic Airway Epithelial Cells. Poster presentation at The International Conference of the American Thoracic Society, San Francisco, CA, USA, May 21-25, 2006.

     

12. Melendez, K., J. Rir-Sima-Ah, Y. A. Mebratu and Y. Tesfaigzi: Noxa, a BH3 Only-Domain Bcl-2 Family Member Delays Cell Growth and Enhances IFNg-, H₂O₂- and UV-Induced Cell Death in Airway Epithelial Cells. Poster presentation at The International Conference of the American Thoracic Society, San Francisco, CA, USA, May 21-25, 2006.

     

13. Mebratu, Y. A., B. Dickey, C. Evans and Y. Tesfaigzi: The BH3-Only Protein Bik Inhibits Nuclear Translocation of Activated ERK to Mediate IFNg-Induced Cell Death in Epithelial Cells. Poster presentation at The International Conference of the American Thoracic Society, Toronto, Canada, May 17-21, 2008.

     

14. Mebratu, Y. A., B. F. Dickey, C. Evans and Y. Tesfaigzi: The BH3-Only Protein Bik/Blk/Nbk Inhibits Nuclear Translocation of Activated ERK1/2 to Mediate IFNg-Induced Cell Death. J. Cell Biol. (accepted).