Seilkop, Steven K., MS

EDUCATION
B.S. (Mathematics), 1972, Miami University
M.S. (Statistics), 1974, Miami University
Advanced Graduate Studies (Biostatistics), 1979-1981, University of North
     Carolina 

 

EMPLOYMENT

2004 - Present Member, Manganese Health Research Program Steering Committee, International Manganese Institute
2002 - Present Adjunct Scientist, Lovelace Respiratory Research Institute, Albuquerque, NM
2001 - Present Core Investigator, National Environmental Respiratory Center, Albuquerque, NM
1995 - Present Proprietor/Consulting Biostatistician, SKS Consulting Services, Siler City, NC
1983 - 1995 President, Director of Statistical Services, Analytical Sciences, Inc., Research Triangle Park, NC
1982 - 1983 Program Manager/Biostatistician, Program Resources, Inc., Research Triangle Park, NC
1980 - 1982 Mathematical Statistician, U.S. EPA, Atmospheric Sciences Research Laboratory, Research Triangle Park, NC
1979 - 1980 Research Assistant, North Carolina State University
1977 - 1980 Statistical Consultant, U.S. EPA, Health Effects Research Laboratory, Cincinnati, OH
1975 - 1979 Statistical Consultant, Miami University, Oxford, OH
1974 - 1975 Manager, Statistics and Research, Blue Cross of Southwest Ohio, Cincinnati, OH

 

PROFESSIONAL AFFILIATIONS
American Statistical Association, 1974-Present
American Association for the Advancement of Science, 1980-Present
Biometric Society, 1980-Present 

 

AREAS OF RESEARCH
Mr. Seilkop has been a statistical consultant in governmental, industrial, and academic settings for more than 25 years. His career has encompassed both collaborative and original research in diverse scientific disciplines, including toxicology, epidemiology, and atmospheric science. He has served as Principal Investigator on statistical support contracts with the National Institute of Environmental Health Sciences, U.S. Environmental Protection Agency, and National Oceanic and Atmospheric Administration, where he applied and developed statistical methods for carcinogenicity and toxicity testing in animals, evaluation of spatial and temporal patterns of air pollution, and human health risk assessment. At present, he is engaged in collaborative research with toxicologists at LRRI studying the effects of various types of air contaminants on animals, and for other clients he is developing approaches to integrate the results of animal-based toxicological research and human epidemiological studies in quantitative assessments of human health risk. 

 

REPRESENTATIVE PUBLICATIONS

  1. Mauderly, J. L., A. P. Gigliotti, E. B. Barr, W. E. Bechtold, S. A. Belinsky, F. F. Hahn, C. H. Hobbs, T. H. March, S. K. Seilkop and G. L. Finch: Chronic Inhalation Exposure to Mainstream Cigarette Smoke Increases Lung and Nasal Tumor Incidence in Rats. Toxicol. Sci. 81(2): 280-292, 2004.

     

  2. McDonald, J. D., K. S. Harrod, JC. Seagrave, S. K. Seilkop and J. L. Mauderly: Effects of Low Sulfur Fuel and a Catalyzed Particle Trap on the Composition and Toxicity of Diesel Emissions. Environ. Health Perspect. 112(13): 1307-1312, 2004.

     

  3. Meng, Q., D. M. Walker, B. R. Scott, S. K. Seilkop, J. K. Aden and V. E. Walker: Characterization of Hprt Mutations in cDNA and Genomic DNA of T-Cell Mutants from Control and 1,3-Butadiene-Exposed Male B6C3F1 Mice and F344 Rats. Environ. Mol. Mutagen. 43: 75-95, 2004.

     

  4. Reed, M. D., A. P. Gigliotti, J. D. McDonald, JC. Seagrave, S. K. Seilkop and J. L. Mauderly: Health Effects of Subchronic Exposure to Environmental Levels of Diesel Exhaust. Inhal. Toxicol. 16: 177-193, 2004.

     

  5. Walker, D. M., S. K. Seilkop, B. R. Scott and V. E. Walker: Hprt Mutant Frequencies in Splenic T-Cells of Male F344 Rats Exposed by Inhalation to Propylene. Environ. Mol. Mutagen. 43: 265-272, 2004.

     

  6. Harrod, K. S., R. J. Jaramillo, J. A. Berger, A. P. Gigliotti, S. K. Seilkop and M. D. Reed: Inhaled Diesel Engine Emissions Reduce Bacterial Clearance and Exacerbate Lung Disease to Pseudomonas aeruginosa Infection In Vivo. Toxicol. Sci. 83(1): 155-165, 2005.

     

  7. Hutt, J. A., B. R. Vuillemenot, E. B. Barr, M. J. Grimes, F. F. Hahn, C. H. Hobbs, T. H. March, A. P. Gigliotti, S. K. Seilkop, G. L. Finch, J. L. Mauderly and S. A. Belinsky: Life-Span Inhalation Exposure to Mainstream Cigarette Smoke Induces Lung Cancer in B6C3F1 Mice Through Genetic and Epigenetic Pathways. Carcinogenesis 26(11): 1999-2009, 2005.

     

  8. Reed, M. D., L. F. Blair, K. Burling, I. Daly, A. P. Gigliotti, R. Gudi, M. D. Mercieca, J. D. McDonald, D. J. Naas, J. P. O'Callaghan, S. K. Seilkop, N. L. Ronsko, V. O. Wagner and R. C. Kraska: Health Effects of Subchronic Inhalation of Diesel-Water Emulsion Emissions. Inhal. Toxicol. 17(14): 851-870, 2005.

     

  9. Seagrave, J., A. Gigliotti, J. D. McDonald, S. K. Seilkop, K. A. Whitney, B. Zielinska and J. L. Mauderly: Composition, Toxicity, and Mutagenicity of Particulate and Semivolatile Emissions from Heavy-Duty Compressed Natural Gas-Powered Vehicles. Toxicol. Sci. 87(1): 232-241, 2005.

     

  10. Seagrave, JC., J. D. McDonald, M. D. Reed, S. K. Seilkop and J. L. Mauderly: Responses to Subchronic Inhalation of Low Concentrations of Diesel Exhaust and Hardwood Smoke Measured in Rat Bronchoalveolar Lavage Fluid. Inhal. Toxicol 17: 657-670, 2005.

     

  11. Barrett, E. G., R. D. Henson, S. K. Seilkop, J. D. McDonald and M. D. Reed: Effects of Hardwood Smoke Exposure on Allergic Airway Inflammation in Mice.Inhal. Toxicol. 18(1): 33-43, 2006.

     

  12. Reed, M. D., L. F. Blair, K. Burling, I. Daly, A. P. Gigliotti, R. Gudi, M. D. Mercieca, J. D. McDonald, J. P. O'Callaghan, S. K. Seilkop, N. L. Ronsko, V. O. Wagner and R. C. Kraska: Health Effects of Subchronic Exposure to Diesel-Water-Methanol Emulsion Emissions. Toxicol. Ind. Health 22(2): 65-85, 2006.

     

  13. Reed, M. D., M. J. Campen, A. P. Gigliotti, K. S. Harrod, J. D. McDonald, JC. Seagrave, J. L. Mauderly and S. K. Seilkop: Health Effects of Subchronic Exposure to Environmental Levels of Hardwood Smoke. Inhal. Toxicol. 18(8): 523-539, 2006.

     

  14. Seagrave, JC., J. D. McDonald, E. Bedrick, E. S. Edgerton, A. P. Gigliotti, J. J. Jansen, L. Ke, L. P. Naeher, S. K. Seilkop, M. Zheng and J. L. Mauderly: Lung Toxicity of Ambient Particulate Matter from Southeastern U.S. Sites with Different Contributing Sources: Relationships Between Composition and Effects.Environ. Health Perspect. 114(9): 1387-1393, 2006.

     

  15. Meng, Q., D. M. Walker, J. D. McDonald, R. F. Henderson, M. M. Carter, D. L. Cook, Jr., C. L. McCash, S. M. Torres, M. J. Bauer, S. K. Seilkop, P. B. Upton, N. I. Georgieva, G. Boysen, J. A. Swenberg and V. E. Walker: Age-, Gender-, and Species-Dependent Mutagenicity in T Cells of Mice and Rats Exposed by Inhalation to 1,3-Butadiene. Chem. Biol. Interact. 166(1-3): 121-131, 2007.

     

  16. Walker, D. M., D. E. Malarkey, S. K. Seilkop, F. A. Ruecker, K. A. Funk, M. J. Wolfe, C. P. Treanor, J. F. Foley, F. F. Hahn, J. F. Hardisty and V. E. Walker: Transplacental Carcinogenicity of 3¢-Azido-3¢-deoxythymidine in B6C3F1 Mice and F344 Rats. Environ. Mol. Mutagen. 48(3-4): 283-298, 2007.

     

  17. Walker, D. M., J. D. McDonald, Q. Meng, D. A. Kracko, M. J. Bauer, S. K. Seilkop, E. L. Walker, R. F. Henderson and V. E. Walker: Measurement of Plasma or Urinary Metabolites and Hprt Mutant Frequencies Following Inhalation Exposure of Mice and Rats to 3-Butene-1,2-diol. Chem. Biol. Interact. 166(1-3): 191-206, 2007.

 

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