Pitt, M. Louise M., PhD

EDUCATION
B.S. (Microbiology and Biochemistry) 1974, University of Cape Town, South
     Africa
B.S. with Honors (Virology and Immunology) 1978, University of Witwatersrand,
     South Africa
Ph.D. (Respiratory Immunology) 1986, University of Witwatersrand, South Africa
 


EMPLOYMENT

2007 - Present Adjunct Senior Scientist, Lovelace Respiratory Research Institute, Albuquerque, NM
2004 - Present Director, Center for Aerobiological Sciences, USAMRIID, Fort Detrick, Frederick, MD
1995 - 2004 Chief, Department of Aerobiology and Product Evaluation, Toxinology and Aerobiology Division, USAMRIID, Fort Detrick, Frederick, MD
1990 - 1995 Aerobiological Scientist, Department of Aerobiology, Toxinology Division, USAMRIID, Fort Detrick, Frederick, MD
1987 - 1990 Associate of the National Research Council (NRC) of the National Academy of Sciences in the Department of Respiratory and Mucosal Immunity, USAMRIID, Fort Detrick, Frederick, MD
1986 - 1987 Visiting Scientist, Laboratory of Respiratory and Mucosal Immunity, USAMRIID, Fort Detrick, Frederick, MD
1984 - 1987 Head, Section of Immunology and Microbiology, National Centre for Occupational Health (NCOH), Johannesburg, South Africa
1981 - 1984 Department Head, Department of Immunology, NCOH, Johannesburg, South Africa
1980 - 1981 Senior Professional Officer, Department of Immunology, NCOH, Johannesburg, South Africa
1976 - 1980 Professional Officer, Department of Immunology, National Research Institute for Occupational Diseases of the Medical Research Council [which subsequently became the National Centre for Occupational Health (NCOH) in April 1979], Johannesburg, South Africa



REPRESENTATIVE PUBLICATIONS

  1. Pitt, M. L., S. F. Little, B. E. Ivins, P. Fellows, J. Barth, J. Hewetson, P. Gibbs, M. Dertzbaugh and A. M. Friedlander: In Vitro Correlate of Immunity in a Rabbit Model of Inhalational Anthrax. Vaccine 19: 4768-4773, 2001.

     

  2. Waag, D. M., M. J. England, R. F. Tammariello, W. R. Byrne, P. Gibbs, C. M. Banfield and M. L. Pitt: Comparative Efficacy and Immunogenicity of Q Fever Chloroform:Methanol Residue (CMR) and Phase I Cellular (Q-Vax) Vaccines in Cynomolgus Monkeys Challenged by Aerosol. Vaccine 20: 2623-2634, 2002.

     

  3. Welkos, S., M. L. Pitt, M. Martinez, A. Friedlander, P. Vogel and R. Tammariello: Determination of the Virulence of the Pigmentation-Deficient and Pigmentation-/Plasminogen Activator-Deficient Strains of Yersinia pestis in Non-human Primate and Mouse Models of Pneumonic Plague. Vaccine 20: 2206-2214, 2002.

     

  4. Boles, J. W., M. L. Pitt, R. D. LeClaire, P. H. Gibbs, E. Torres, B. Dyas, R. G. Ulrich and S. Bavari: Generation of Protective Immunity by Inactivated Recombinant Staphylococcal Enterotoxin B Vaccine in Nonhuman Primates and Identification of Correlates of Immunity. Clin. Immunol. 108: 51-59, 2003.

     

  5. Boles, J. W., M. L. Pitt, R. D. LeClaire, P. H. Gibbs, R. G. Ulrich and S. Bavari: Correlation of Body Temperature with Protection Against Staphylococcal Enterotoxin B Exposure and Use in Determining Vaccine Dose-Schedule. Vaccine 21: 2791-2796, 2003.

     

  6. DaSilva, L., D. Cote, C. Roy, M. Martinez, S. Duniho, M. L. Pitt, T. Downey and M. Dertzbaugh: Pulmonary Gene Expression Profiling of Inhaled Ricin.Toxicon 41: 813-822, 2003.

     

  7. Manabe, Y. C., A. M. Dannenberg, Jr., S. K. Tyagi, C. L. Hatem, M. Yoder, S. C. Woolwine, B. C. Zook, M. L. Pitt and W. R. Bishai: Different Strains of Mycobacterium Tuberculosis Cause Varied Spectrums of Disease in the Rabbit Model of Tuberculosis. Infect. Immun. 71: 6004-6011, 2003.

     

  8. Roy, C. J., M. Hale, J. M. Hartings, L. Pitt and S. Duniho: Impact of Inhalation Exposure Modality and Particle Size on the Respiratory Deposition of Ricin in BALB/c Mice. Inhal. Toxicol. 15: 619-638, 2003.

     

  9. Dorman, S. E., C. L. Hatem, S. Tyagi, K. Aird, J. Lopez-Molina, M. L. Pitt, B. C. Zook, A. M. Dannenberg, Jr., W. R. Bishai and Y. C. Manabe: Susceptibility to Tuberculosis: Clues from Studies with Inbred and Outbred New Zealand White Rabbits. Infect. Immun. 72: 1700-1705, 2004.

     

  10. LeClaire, R. D. and M. L. M. Pitt: Chapter 3, Biological Weapons Defense: Effect Levels. In Biological Weapons Defense: Infectious Disease and Counterbioterrorism, pp. 41-62, Human Press, 2004.

     

  11. Little, S. F., B. E. Ivins, P. F. Fellows, M. L. Pitt, S. L. Norris and G. P. Andrews: Defining a Serological Correlate of Protection in Rabbits for a Recombinant Anthrax Vaccine. Vaccine 22: 422-430, 2004.

     

  12. Mense, M. G., R. H. Borschel, C. L. Wilhelmsen, M. L. Pitt and D. L. Hoover: Pathologic Changes Associated with Brucellosis Experimentally Induced by Aerosol Exposure in Rhesus Macaques (Macaca mulatta). Am. J. Vet. Res. 65: 644-652, 2004.

     

  13. Pitt, M. L. M. and R. D. LeClaire: Chapter 4, Pathogenesis by Aerosol. In Biological Weapons Defense: Infectious Disease and Counterbioterrorism, pp. 65-78, Human Press, 2004.

     

  14. Kesavan, A. K., S. E. Mendez, C. L. Hatem, J. Lopez-Molina, K. Aird, M. L. Pitt, A. M. Dannenberg, Jr. and Y. C. Manabe: Effects of Dexamethasone and Transient Malnutrition on Rabbits Infected with Aerosolized Mycobacterium Tuberculosis CDC1551. Infect. Immun. 73: 7056-7060, 2005.

     

  15. Boles, J., M. West, V. Montgomery, R. Tammariello, M. L. Pitt, P. Gibbs, L. Smith and R. D. LeClaire: Recombinant C Fragment of Botulinum Neurotoxin B Serotype (rBoNTB (HC)) Immune Response and Protection in the Rhesus Monkey. Toxicon 47: 877-884, 2006.

     

  16. Hepler, R. W., R. Kelly, T. B. McNeely, H. Fan, M. C. Losada, H. A. George, A. Woods, L. D. Cope, A. Bansal, J. C. Cook, G. Zang, S. L. Cohen, X. Wei, P. M. Keller, E. Leffel, J. G. Joyce, L. Pitt, L. D. Schultz, K. U. Jansen and M. Kurtz: A Recombinant 63-kDa Form of Bacillus Anthracis Protective Antigen Produced in the Yeast Saccharomyces Cerevisiae Provides Protection in Rabbit and Primate Inhalational Challenge Models of Anthrax Infection. Vaccine 24: 1501-1514, 2006.

     

  17. Jones, T., J. J. Adamovicz, S. L. Cyr, C. R. Bolt, N. Bellerose, L. M. Pitt, G. H. Lowell and D. S. Burt: Intranasal Protollin/F1-V Vaccine Elicits Respiratory and Serum Antibody Responses and Protects Mice Against Lethal Aerosolized Plague Infection. Vaccine 24: 1625-1632, 2006.

     

  18. Leffel, E. K. and L. M. Pitt: Chapter 6, Anthrax. In Biodefense: Research Methodology and Animal Models (J. R. Swearengen, ed.), pp. 77-94, CRC Press, 2006.

     

  19. Little, S. F., B. E. Ivins, W. M. Webster, P. F. Fellows, M. L. Pitt, S. L. Norris and G. P. Andrews: Duration of Protection of Rabbits After Vaccination with Bacillus Anthracis Recombinant Protective Antigen Vaccine. Vaccine 24: 2530-2536, 2006.

     

  20. Roy, C. J. and L. M. Pitt: Chapter 5, Infectious Disease Aerobiology: Aerosol Challenge Methods. In Biodefense: Research Methodology and Animal Models(J. R. Swearengen, ed.), pp. 61-76, CRC Press, 2006.

     

  21. Gamble, C. S., K. O. Jacobsen, E. K. Leffel and M. L. Pitt: Use of a Low-Concentration Heparin Solution to Extend the Life of Central Venous Catheters in African Green Monkeys (Chlorocebus aethiops). J. Am. Assoc. Lab. Anim. Sci. 46: 58-60, 2007.

     

  22. Heine, H. S., J. Basssett, L. Miller, J. M. Hartings, B. E. Ivins, M. L. Pitt, D. Fritz, S. L. Norris and W. R. Byrne: Determination of Antibiotic Efficacy Against Bacillus Anthracis in a Mouse Aerosol Challenge Model. Antimicrob. Agents Chemother. 51: 1373-1379, 2007.

     

  23. Twenhafel, N. A., E. Leffel and M. L. Pitt: Pathology of Inhalational Anthrax Infection in the African Green Monkey. Vet. Pathol. 44: 716-721, 2007.
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