EDUCATION
D.V.M. with High Distinction (Veterinary Medicine) 1966, Colorado State
University
PROFESSIONAL CERTIFICATION (by examination)
Veterinary Medicine, Colorado/Wyoming, 1966
Veterinary Medicine, New Mexico, 1969
Diplomate, American Board of Veterinary Toxicology, 1972
American Board of Toxicology, Certified - General Toxicology, 1981
EMPLOYMENT
|
2008 - Present |
Scientist Emeritus, Lovelace Respiratory Research Institute, Albuquerque, NM |
|
1996 - 2008 |
Director, Toxicology Division; Program Manager, Experimental Toxicology Program; Senior Scientist, Lovelace Respiratory Research Institute; Vice-President, Lovelace Biomedical and Environmental Research Institute, Albuquerque, NM |
|
1994 - 1996 |
Associate Director, Inhalation Toxicology Research Institute; Vice President, Lovelace Biomedical and Environmental Research Institute, Albuquerque, NM |
|
1986 - Present |
Clinical Professor, College of Pharmacy, University of New Mexico, Albuquerque, NM |
|
1974 - 1993 |
Assistant Director, Inhalation Toxicology Research Institute, Albuquerque, NM |
|
1969 - 1974 |
Toxicologist, Inhalation Toxicology Research Institute, Albuquerque, NM |
|
1966 - 1969 |
Captain, U. S. Army, U. S. Army Medical Research Institute of Infectious Diseases, Fort Detrick, Frederick, MD |
PROFESSIONAL AFFILIATIONS
American Academy of Veterinary and Comparative Toxicology (Sec/Treas.,
1977-1981)
American Veterinary Medical Association
New Mexico Veterinary Medical Association
Phi Kappa Phi
Phi Zeta
Radiation Research Society
Society of Toxicology, Inhalation Specialty Section; Veterinary Specialty Section;
President, 1995-1996; Risk Assessment Specialty Section; Mountain West
Chapter
Committee on Toxicology, Board of Environmental Studies and Toxicology,
Commission on Life Sciences (BEST), National Research Council, Member
1999-Present
National Associate of the National Academics, 2001-Present
AREAS OF RESEARCH
Dr. Hobbs' primary research interests are the long-term biological effects of inhaled materials and the mechanisms by which they occur. His experience covers inhaled nuclear and chemical toxicants as well as infectious diseases. Research in these areas has ranged from physical and chemical characterization of airborne toxicants to in vitro mechanistic and toxicologic studies and long-term studies in laboratory animals of the relationships between dose to critical tissues and resulting biological effects and the important mechanisms active in determining these relationships. Dr. Hobbs has also been heavily involved in research management. He has focused on the direction and use of multidisciplinary teams of personnel to address complex problems
ACCESS THIS AUTHOR'S PUBLICATIONS IN PUBMED
REPRESENTATIVE PUBLICATIONS
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Morrow, P. E., J. K. Haseman, C. H. Hobbs, K. E. Driscoll, V. Vu and G. Oberdoerster: The Maximum Tolerated Dose for Inhalation Bioassays: Toxicity vs. Overload. Fundam. Appl. Toxicol. 29: 155-167, 1996.
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Finch, G. L., D. L. Lundgren, E. B. Barr, B. T. Chen, W. C. Griffith, C. H. Hobbs, M. D. Hoover, K. J. Nikula and J. L. Mauderly: Chronic Cigarette Smoke Exposure Increases the Pulmonary Retention and Radiation Dose of239Pu Inhaled as 239PuO2 by F344 Rats. Health Phys. 75(6): 597-609, 1998.
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Finch, G. L., T. March, F. F. Hahn, E. B. Barr, S. A. Belinsky, M. D. Hoover, J. F. Lechner, K. J. Nikula and C. H. Hobbs: Carcinogenic Responses of Transgenic Heterozygous p53 Knockout Mice to Inhaled 239PuO2 or Metallic Beryllium. Toxicol. Pathol. 24(4): 484-491, 1998.
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March, T. H., E. B. Barr, G. L. Finch, F. F. Hahn, C. H. Hobbs, M. G. Ménache and K. J. Nikula: Cigarette Smoke Exposure Produces More Evidence of Emphysema in B6C3F1 Mice than in F344 Rats. Toxicol. Sci. 51: 289-299, 1999.
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Hahn, F., G. Finch, S. Belinsky, E. Barr, C. Hobbs, M. Hoover, K. Nikula and J. Mauderly: Biomarkers in Exposures to Cigarette Smoke and Radiation. In Radiation Research. Volume 2: Proceedings (M. Moriarty, C. Mothersill, C. Seymour, M. Edington, J. F. Ward and R. J. M. Fry, eds.), pp. 456-458, Allen Press, Inc., Lawrence, KS, 2000.
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Finch, G. L., C. H. Hobbs, L. F. Blair, E. B. Barr, F. F. Hahn, R. J. Jaramillo, J. E. Kubatko, T. H. March, R. K. White, J. R. Krone, M. G. Ménache, K. J. Nikula, J. L. Mauderly, J. Van Gerpen, M. D. Merceica, B. Zielinska, L. Stankowski, K. Burling and S. Howell: Effects of Subchronic Inhalation Exposure of Rats to Emissions from a Diesel Engine Burning Soybean Oil-Derived Biodiesel Fuel. Inhal. Toxicol. 14(10): 1017-1048, 2002.
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Cherrington, A. D., D. W. Neal, D. S. Edgerton, D. Glass, L. Bowen, C. H. Hobbs, C. Leach, R. Rosskamp and T. R. Strack: Inhalation of Insulin in Dogs: Assessment of Insulin Levels and Comparison to Subcutaneous Injection. Diabetes 53: 877-881, 2004.
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Mauderly, J. L., A. P. Gigliotti, E. B. Barr, W. E. Bechtold, S. A. Belinsky, F. F. Hahn, C. H. Hobbs, T. H. March, S. K. Seilkop and G. L. Finch: Chronic Inhalation Exposure to Mainstream Cigarette Smoke Increases Lung and Nasal Tumor Incidence in Rats. Toxicol. Sci. 81(2): 280-292, 2004.
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Deshpande, D. S., J. D. Blanchard, J. Schuster, D. Fairbanks, C. Hobbs, R. Beihn, C. Densmore, S. Farr and I. Gonda: Gamma Scintigraphic Evaluation of a Miniaturized AERx® Pulmonary Delivery System for Aerosol Delivery to Anesthetized Animals Using a Positive Pressure Ventilation System. J. Aerosol Med. 18(1): 34-44, 2005.
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Edgerton, D. S., D. W. Neal, M. Scott, L. Bowen, W. Wilson, C. H. Hobbs, C. Leach, S. Sivakumaran, T. R. Strack and A. D. Cherrington: Inhalation of Insulin (Exubera) is Associated with Augmented Disposal of Portally Infused Glucose in Dogs. Diabetes 54: 1164-1170, 2005.
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Hutt, J. A., B. R. Vuillemenot, E. B. Barr, M. J. Grimes, F. F. Hahn, C. H. Hobbs, T. H. March, A. P. Gigliotti, S. K. Seilkop, G. L. Finch, J. L. Mauderly and S. A. Belinsky: Life-Span Inhalation Exposure to Mainstream Cigarette Smoke Induces Lung Cancer in B6C3F1 Mice Through Genetic and Epigenetic Pathways. Carcinogenesis 26(11): 1999-2009, 2005.
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March, T. H., L. E. Bowen, G. L. Finch, K. J. Nikula, B. J. Wayne and C. H. Hobbs: Effects of Strain and Treatment with Inhaled All-Trans-Retinoic Acid on Cigarette Smoke-Induced Pulmonary Emphysema in Mice. COPD: Jnl. Chron. Obstruct. Dis. 3: 289-302, 2005.
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Edgerton, D. S., A. D. Cherrington, P. Williams, D. W. Neal, M. Scott, L. Bowen, W. Wilson, C. H. Hobbs, C. Leach, M. C. Kuo and T. R. Strack: Inhalation of Human Insulin (Exubera) Augments the Efficiency of Muscle Glucose Uptake In Vivo. Diabetes 55(12): 3604-3610, 2006.
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Edgerton, D. S., K. M. Stettler, D. W. Neal, M. Scott, L. Bowen, W. Wilson, C. H. Hobbs, C. Leach, T. R. Strack, and A. D. Cherrington: Inhalation of Human Insulin is Associated with Improved Insulin Action Compared with Subcutaneous Injection and Endogenous Secretion in Dogs. J. Pharmacol. Exp. Ther. 319(3): 1258-1264, 2006.
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Edgerton, D. S., K. M. S. Johnson, D. W. Neal, M. Scott, C. H. Hobbs, X. Zhang, A. Duttaroy and A. D. Cherrington: Inhibition of Dipeptidyl Peptidase-4 by Vildagliptin During Glucagon-like Peptide-1 Infusion Increases Liver Glucose Uptake in the Conscious Dog. Diabetes (accepted).