EDUCATION
B.S. (Biology) 1994, Kansas State University
Ph.D. (Biomedical Sciences) 2005, University of New Mexico
EMPLOYMENT
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2009 - Present |
Associate Scientist, Cardiopulmonary Physiology, Lovelace Respiratory Research Institute, Albuquerque, NM |
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2005 - 2009 |
Postdoctoral Fellow, Cardiovascular and Respiratory Physiology, Lovelace Respiratory Research Institute, Albuquerque, NM |
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2004 - 2005 |
Instructor (in training), Gross Anatomy for Biomedical Scientist, University of New Mexico, Albuquerque, NM |
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2004 |
Instructor, Receptor-Mediated Toxicology Course, University of New Mexico, Albuquerque, NM |
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2002 |
Teaching Assistant, Health Sciences Academy Summer Program, University of New Mexico, Albuquerque, NM |
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2000 - 2003 |
Teaching Assistant, Pharmacy Lab 731L, University of New Mexico, Albuquerque, NM |
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2000 - 2005 |
Graduate Student/Research Assistant, University of New Mexico, Albuquerque, NM |
|
1995 - 2000 |
Process Development Technician, Microelectricomechanical Systems (MEMS) Department, Microelectronic Developmental Laboratory, Sandia National Laboratory, Albuquerque, NM |
AWARDS
Environmental Protection Agency's (EPA) Science to Achieve Results (STAR)
Pre-doctoral Graduate Fellowship, 2003-2005
American Society for Pharmacology and Experimental Therapeutics (ASPET)
Graduate Student Travel Award, 2003
Society of Toxicology Graduate Student Travel Award, 2004
American Society for Pharmacology and Experimental Therapeutics (ASPET)
Graduate Student Travel Award, 2004
Mountain West Society of Toxicology Student Platform Presentation Award
(2nd place), 2004
National Institute of Health NRSA Postdoctoral Fellowship, 2006-2008
SOT Inhalation and Respiratory Specialty Section Post-doctoral Award, 2007
SOT Inhalation and Respiratory Specialty Section Publication of the Year Award, 2008
National Institute of Health Pathway to Independence Award (K99-R00), 2008-2012
PROFESSIONAL AFFILIATIONS
The American Physiological Society
Society of Toxicology
American Heart Association
American Society for Pharmacology and Experimental Therapeutics
AREAS OF RESEARCH
Dr. Lund’s primary research interests include investigating the mechanisms and physiological pathways involved in the progression of vascular pathologies associated with exposure to environmental pollutants. Specific areas of interest include the contributions of vasoactive peptides (endothelin-1), reactive oxygen species, and expression and activation of matrix metalloproteinases in the development and/or progression of vascular disease, as well as identification of circulating biomarkers which indicate predisposition to a cardio- or cerebro-vascular clinical event. Additionally, Dr. Lund is currently investigating the effects of common environmental pollutants on blood-brain barrier disruption and subsequent toxicity. Dr. Lund is also involved in establishing models of pulmonary hypertension at LRRI.
ACCESS THIS AUTHOR'S PUBLICATIONS IN PUBMED
REPRESENTATIVE PUBLICATIONS
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Lund, A. K., M. B. Goens, N. Kanagy and M. K. Walker: Cardiac Hypertrophy in Aryl Hydrocarbon (AhR) Null Mice is Associated with Elevated Angiotensin II, Endothelin-1 and Mean Arterial Blood Pressure. Toxicol. Appl. Pharmacol. 193: 177-187, 2003.
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Thackaberry, E. A., E. J. Bedrick, M. B. Goens, L. Danielson, A. K. Lund, D. Gabaldon, S. M. Smith and M. K. Walker: Insulin Regulation in AhR-Null Mice: Embryonic Cardiac Enlargement, Neonatal Macrosomia, and Altered Insulin Regulation and Response in Pregnant and Again AhR-Null Females. Toxicol. Sci. 76: 407-417, 2003.
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Walker, D. M., M. C. Poirier, M. J. Campen, D. L. Cook, Jr., R. L. Divi, K. Nagashima, A. K. Lund, P. Y. Cossey, F. F. Hahn and V. E. Walker: Persistence of Mitochondrial Toxicity in Hearts of Female B6C3F1 Mice Exposed In Utero to 3¢-Azido-3¢-deoxythymidine. Cardiovasc. Toxicol. 4(2): 133-154, 2004.
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Lund, A. K., S. L. Peterson, G. S. Timmins and M. K. Walker: Endothelin-1-Mediated Increase in Reactive Oxygen Species and NADPH Oxidase Activity in Hearts of Aryl Hydrocarbon Receptor (AhR) Null Mice. Toxicol. Sci. 88(1): 265-273, 2005.
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Lund, A. K., M. B. Goens, B. A. Nunez and M. K. Walker: Characterizing the Role of Endothelin-1 in the Progression of Cardiac Hypertrophy in Aryl Hydrocarbon Receptor (AhR) Null Mice. Toxicol. Appl. Pharmacol. 212(2): 127-135, 2006.
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Lund, A. K., T. L. Knuckles, C. Obot Akata, R. Shohet, J. D. McDonald, A. Gigliotti, JC. Seagrave and M. J. Campen: Gasoline Exhaust Emissions Induce Vascular Remodeling Pathways Involved in Atherosclerosis. Toxicol. Sci. 95(2): 485-494, 2007.
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Knuckles, T. L., A. K. Lund, S. N. Lucas and M. J. Campen: Diesel Exhaust Exposure Enhances Venoconstriction via Uncoupling of eNOS. Toxicol. Appl. Pharmacol. 230(3): 346-351, 2008.
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Lund, A. K., L. N. Agbor, N. Zhang, A. Baker, H. Zhao, G. D. Fink, N. L. Kanagy and M. K. Walker: Loss of the Aryl Hydrocarbon Receptor Induces Hypoxemia, Endothelin-1, and Systemic Hypertension at Modest Altitude. Hypertension 51(3): 803-809, 2008.
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Lund, A. K., J. Lucero, S. Lucas, M. C. Madden, J. D. McDonald, JC. Seagrave, T. L. Knuckles and M. J. Campen: Vehicular Emissions Induce Vascular MMP-9 Expression and Activity Associated with Endothelin-1 Mediated Pathways. Arterioscler. Thromb. Vasc. Biol. 29(4): 511-517, 2009.
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McDonald, J. D., M. Doyle-Eisele, M. J. Campen, JC. Seagrave, T. Holmes, A. Lund, J. D. Surratt, J. H. Seinfeld, A. C. Rohr and E. M. Knipping: Cardiopulmonary Response to Inhalation of Biogenic Secondary Organic Aerosol. Inhal. Toxicol. (in press).
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Campen, M. J., A. K. Lund, T. L. Knuckles, D. J. Conklin, B. Bishop, D. Young, S. K. Seilkop, JC. Seagrave, M. D. Reed and J. D. McDonald: Inhaled Diesel Emissions Alter Atherosclerotic Plaque Composition in ApoE-/- Mice. Toxicol. Appl. Pharmacol. (in press).